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Thermo Scientific™ EZ-Link™ TFP Ester-PEG4-DBCO
An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules.
206.00€ - 279.00€
Specifica
Chemical Reactivity | Amine-Azide |
---|---|
Cleavable | No |
Descrizione | TFP Ester-PEG4-DBCO |
Peso molecolare | 714.7 |
PEGylated | Yes |
Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
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Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
17514346
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Thermo Scientific™
C20039 |
10 x 1 mg |
206.00€
25mg |
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17621586
|
Thermo Scientific™
C20043 |
10 x 1 mg |
279.00€
pezzi 10 |
Spedizione stimata: 22-11-2024
Eseguire il login per visualizzare lo stock disponibile |
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Descrizione
- An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications
- The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules
- Once a protein or (bio)molecule is DBCO labeled, it can undergo a copper-free azide-alkyne cycloaddition reaction to form a stable triazole linkage with an azide labeled coupling partner
- Can be used to create diverse conjugates with the biorthogonal coupling between an alkyne and azide (supplied separately)
- The coupling or crosslinking procedure is typically done in two steps
- First, a protein or amine containing molecule is labeled with a DBCO group and excess crosslinker is removed
- Second, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moiety
- Labeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
- Ragent readily dissolves in water-miscible solvents for dilution into aqueous reaction mixtures
- TFP esters are more hydrolytically stable than NHS esters
Specifica
Amine-Azide | |
TFP Ester-PEG4-DBCO | |
Yes | |
Upon receipt store desiccated at -20°C. | |
Wet Ice | |
Chemical Labeling | |
TFP Ester, DBCO | |
10 x 1 mg | |
Standard, Single-use | |
Crosslinker |
No | |
714.7 | |
17.9 Å | |
Not determined | |
EZ-Link™ No-Weigh™ | |
Heterobifunctional | |
Medium (10 to 30 Å) | |
DMF, DMSO | |
No |