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Invitrogen™ Factor X Monoclonal Antibody (156106)
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Codice prodotto. 30535785
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Quantità:
500 μg
Dimensione della confezione:
500µg
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Codice prodotto. Quantità unitSize
30535785 500 μg 500µg
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Codice prodotto. 30535785 Fornitore Invitrogen™ N. del fornitore MA560900

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Descrizione

Mouse Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Factor X
Applicazioni Immunoprecipitation, Western Blot
Classificazione Monoclonal
Clone 156106
Concentrazione 0.5 mg/mL
Coniugato Unconjugated
Formulazione PBS with trehalose and no preservative
Gene F10
N. accesso geni P00742
Alias gene Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor 10; Factor X heavy chain; Factor X light chain; factor Xa; Factor10; FX; FXA; prothrombinase; RP11-98F14.9; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Simboli geni F10
Specie ospite Mouse
Immunogeno Mouse myeloma cell line NS0-derived recombinant human Coagulation Factor X, Leu24-Lys488 (predicted).
Metodo di purificazione Protein A/G
Quantità 500 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 2159
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Forma Lyophilized
Isotype IgG1
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