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Invitrogen™ Factor X/Xa Monoclonal Antibody (9050)
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Codice prodotto. 11529882
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Quantità:
100 μg
Dimensione della confezione:
100µg
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Codice prodotto. Quantità unitSize
11529882 100 μg 100µg
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Codice prodotto. 11529882 Fornitore Invitrogen™ N. del fornitore MA143035

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Descrizione

Rat Monoclonal Antibody

This antibody detects mouse factor X (heavy chain) and mouse factor Xa (heavy chain) by ELISA and Western blot, and cross-reacts with human factor X/Xa (Western blot only). Western blot can be performed under reducing and non-reducing conditions. Inhibitory properties: Does not inhibit PT (mouse plasma). Purity >95% by SDS-PAGE.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Factor X/Xa
Applicazioni ELISA, Western Blot
Classificazione Monoclonal
Clone 9050
Concentrazione 8 mg/mL
Coniugato Unconjugated
Formulazione 50% water with 50% glycerol and no preservative
Gene F10
N. accesso geni O88947, P00742
Alias gene Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Simboli geni F10
Specie ospite Rat
Immunogeno Purified mouse factor X.
Metodo di purificazione SDS-PAGE
Quantità 100 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 14058, 2159
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Forma Liquid
Isotype IgG
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