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Invitrogen™ Factor X/Xa (Calcium-dependent) Monoclonal Antibody (CaFX-50)
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Codice prodotto. 15303931
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Quantità:
200 μg
Dimensione della confezione:
200µg
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Codice prodotto. Quantità unitSize
15303931 200 μg 200µg
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Codice prodotto. 15303931 Fornitore Invitrogen™ N. del fornitore MA517643

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Descrizione

Mouse Monoclonal Antibody

This antibody is specific for Human Platelet Factors X and Xa in the presence of 5-10 mM CaCl2.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
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Specifica

Antigene Factor X/Xa (Calcium-dependent)
Applicazioni ELISA, Western Blot
Classificazione Monoclonal
Clone CaFX-50
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 0.02% sodium azide
Gene F10
N. accesso geni P00742
Alias gene Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Simboli geni F10
Specie ospite Mouse
Immunogeno Human Factor X purified from the supernatant of thrombin activated platelets.
Metodo di purificazione Protein G
Quantità 200 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 2159
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Forma Liquid
Isotype IgG1
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