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Invitrogen™ Factor X/Xa Polyclonal Antibody
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Codice prodotto. 13200059
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Quantità:
100 μL
Dimensione della confezione:
100µg
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Codice prodotto. Quantità unitSize
13200059 100 μL 100µg
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Codice prodotto. 13200059 Fornitore Invitrogen™ N. del fornitore PA522059

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Descrizione

Rabbit Polyclonal Antibody

Recommended positive controls: rat liver, human F10-transfected 293T cells. Predicted reactivity: Rhesus Monkey (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Factor X/Xa
Applicazioni Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene F10
N. accesso geni P00742, Q63207
Alias gene Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Simboli geni F10
Specie ospite Rabbit
Immunogeno Recombinant protein encompassing a sequence within the center region of human Factor X. The exact sequence is proprietary.
Metodo di purificazione Antigen affinity chromatography
Quantità 100 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 2159, 29243
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Forma Liquid
Isotype IgG
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