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Invitrogen™ Factor X/Xa Polyclonal Antibody
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Codice prodotto. 16668884
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Quantità:
100 μL
Dimensione della confezione:
100µL
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Codice prodotto. Quantità unitSize
16668884 100 μL 100µL
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Codice prodotto. 16668884 Fornitore Invitrogen™ N. del fornitore PA5102412

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Descrizione

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Factor X.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Factor X/Xa
Applicazioni Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene F10
N. accesso geni O88947, P00742, Q63207
Alias gene Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Simboli geni F10
Specie ospite Rabbit
Immunogeno A synthesized peptide derived from human F10(Accession P00742), corresponding to amino acid residues A444-K488.
Metodo di purificazione Affinity chromatography
Quantità 100 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 14058, 2159, 29243
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Forma Liquid
Isotype IgG
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