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Invitrogen™ Factor X/Xa Recombinant Rabbit Monoclonal Antibody (058)
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Codice prodotto. 16364064
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Quantità:
100 μL
Dimensione della confezione:
100µL
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Codice prodotto. Quantità unitSize
16364064 100 μL 100µL
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Codice prodotto. 16364064 Fornitore Invitrogen™ N. del fornitore MA530535

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Descrizione

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human Coagulation Factor X/F10.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Factor X/Xa
Applicazioni ELISA
Classificazione Recombinant Monoclonal
Clone 058
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with no preservative
Gene F10
N. accesso geni P00742
Alias gene Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Simboli geni F10
Specie ospite Rabbit
Immunogeno Recombinant Human Coagulation Factor X/F10 Protein (Met1-Lys488).
Metodo di purificazione Protein A
Quantità 100 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 2159
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Forma Liquid
Isotype IgG
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