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FGF4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA520483

369.35 EUR valido fino al 2025-03-29
Usa il codice promo "24111" per avere il tuo prezzo promozionale.

Codice prodotto. 12838662

  • 554.00€ / 100µg

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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”24111” to get your promotional price

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Descrizione

Descrizione

A suggested positive control is NIH-3T3 cell lysate. PA5-20483 can be used with blocking peptide PEP-0603.

Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
TRUSTED_SUSTAINABILITY
Specifica

Specifica

FGF4
Polyclonal
Unconjugated
Fgf4
FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; heparin-binding growth factor 1; heparin-binding growth factor 4; HST; Hst1; hst-1; HSTF1; HSTF-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; transforming protein KS3
Rabbit
Antigen affinity chromatography
RUO
14175, 2249
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Liquid
Immunocytochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P08620, P11403
Fgf4
An 18 amino acid peptide near the carboxy terminus of the human FGF4.
100 μg
Primary
Human, Mouse
Antibody
IgG
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