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Histone H1 Antibody (HH1/957) - IHC-Prediluted, Novus Biologicals™
Mouse Monoclonal Antibody
Marke: Novus Biologicals NBP2-48087
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Beschreibung
Histone H1 Monoclonal specifically detects Histone H1 in Human, Mouse, Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Spezifikation
| Histone H1 | |
| Monoclonal | |
| Unconjugated | |
| 1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
| H1-1 | |
| Recombinant full-length human Histone H1 protein | |
| 7 mL | |
| Cellular Markers, Chromatin Research, Epigenetics, Histones and Modified Histones, Nuclear Envelope Markers | |
| 3024 | |
| Human, Mouse, Rat | |
| Purified |
| Immunohistochemistry (Paraffin) | |
| HH1/957 | |
| Immunohistochemistry-Paraffin | |
| H1 histone family, member 1, H1.1, H1A, H1F1HIST1, histone 1, H1a, histone cluster 1, H1a, histone H1.1, MGC126642, MGC138345 | |
| Mouse | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation. | |
| Store at 4C. | |
| IgG2a κ |
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