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Proteintech™ HumanKine™ Recombinant Human R-Spondin-I Protein
Sfoglia Tutto Proteintech ProdottiDescrizione
R-Spondin 1 is an approximately 40kDA, glycosylated protein that serves as a major agonist of the Wnt signaling pathway. It regulates the turnover of the LRP6 co-receptor by preventing its internalization by DKK-1. It also promotes stem cell turnover in the mammary glands, intestine, colon, and kidneys. Increased R-Spondin 1 expression has been linked to growth and migration of ovarian cancer cells as well as decreased sensitivity of gliomas to radiation-based therapies (PMID: 17804805, 22439850, 32749219, 30572097).
Specifica
Specifica
| ID gene (immissione) | 284654 |
| Quantità | 10 μg |
| Sorgente | Human |
| Concentrazione di endotossine | <1 EU/μg |
| Reattività specifica | Human |
| Massa | 40 kDa |
| Forma | Lyophilized |
| Purity or Quality Grade | >95% |
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