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Invitrogen™ IL4R Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA536522
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Descrizione
This antibody detects endogenous protein at a molecular weight of 88 kDa. Purity is >95% by SDS-PAGE.
IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.
Specifica
| IL4R | |
| Polyclonal | |
| Unconjugated | |
| IL4R | |
| 582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3566 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| P24394 | |
| IL4R | |
| Synthetic peptide corresponding to amino acids 220-265 of human IL-4R alpha. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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