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Invitrogen™ JMJD1C Polyclonal Antibody
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Rabbit Polyclonal Antibody

Marca:  Invitrogen™ PA520804

Codice prodotto. 12828982

  • 516.00€ / 100µg

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Descrizione

Descrizione

A suggested positive control is human liver tissue lysate. PA5-20804 can be used with blocking peptide PEP-0918.

The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.
TRUSTED_SUSTAINABILITY
Specifica

Specifica

JMJD1C
Polyclonal
Unconjugated
JMJD1C
5430433L24Rik; D630035I23Rik; DKFZp761F0118; FLJ14374; Jhdm2c; JMJD1C; Jmjdic; jumonji domain containing 1C; jumonji domain-containing protein 1C; Kiaa1380; Pr2; Probable JmjC domain-containing histone demethylation protein 2C; RP11-10C13.2; thyroid hormone receptor interactor 8; thyroid receptor-interacting protein 8; TR-interacting protein 8; TRIP8; TRIP-8
Rabbit
Antigen affinity chromatography
RUO
108829, 171120, 221037
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Liquid
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q15652, Q69ZK6
JMJD1C
A 20 amino acid peptide from near the amino terminus of human JMJD1C.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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