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LGI2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA520492
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Descrizione
A suggested positive control is 293 cell lysate. PA5-20492 can be used with blocking peptide PEP-0612.
The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.
Specifica
| LGI2 | |
| Polyclonal | |
| Unconjugated | |
| Lgi2 | |
| Kiaa1916; leucine rich repeat LGI family member 2; leucine-rich glioma-inactivated protein 2; Leucine-rich repeat LGI family member 2; leucine-rich repeat LGI family, member 2; leucine-rich, glioma inactivated 2; LGI1-like protein 2; Lgi2; LGIL2; mKIAA1916 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 246316, 305417, 55203 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q8K4Z0, Q8N0V4 | |
| Lgi2 | |
| a 11 amino acid peptide from near the amino terminus of human LGI2. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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