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Eurofins DiscoverX Met (M1268T) Protein, Active
Descrizione
MET tyrosine kinase is a high-affinity receptor for hepatocyte growth factor/scatter factor. Signaling via this receptor-ligand pair has been shown to affect a wide range of biological activities, including angiogenesis, cellular motility, growth, invasion, and morphogenic differentiation. Mutations in the MET tyrosine kinase receptor have been identified in both hereditary and sporadic forms of papillary renal carcinoma and implicated in tumor growth, invasion, and metastasis.
GenBank J02958. The recombinant protein contains the amino acid substitutions A1209G and V1290L with reference toGenBank J02958. Both substitutions are reported inGenBank BU595386, BQ315895 and BQ316491.
Specifica
Specifica
| Formulazione | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Peso molecolare | 50.1 kDa |
| Quantità | 10 μg |
| Specie | Human |
| Recombinant | Recombinant |
| Tag proteine | N-terminal 6His |
| Sistema di espressione | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Truncated |
| Purity or Quality Grade | ≥54% |
| Proteine | Met (M1268T), active |
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