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MyD88 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA519919
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Descrizione
A suggested positive control is Jurkat cell lysate. PA5-19919 can be used with blocking peptide PEP-0045. The PA5-19919 immunogen is located within the last 50 amino acids of MYD88. Predicted molecular ∽ 35kD. In Western blot applications, this antibody has been observed to detect a band at: 35kD Predicted species reactivity based on immunogen sequence: Pig: (94%), Sheep: (82%), Bovine: (82%), Chicken: (82%)
Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.
Specifica
| MyD88 | |
| Polyclonal | |
| Unconjugated | |
| MYD88 | |
| mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 17874, 301059, 4615 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunocytochemistry, Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P22366, Q6Y1S1, Q99836 | |
| MYD88 | |
| A 17 amino acid peptide near carboxy terminus of human MYD88 isoform 1 | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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