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NALP11 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA521026

Codice prodotto. 12849172

  • 520.00€ / 100µg

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Descrizione

Descrizione

A suggested positive control is Hela cell lysate. PA5-21026 can be used with blocking peptide PEP-1140.

NALP11 is a 1033 amino acid containing cytoplasmic protein belonging to the NLRP family with a DAPIN domain, six LRR (leucine-rich) repeats and a NACHT domain. Reports suggest that it is a short NALP involved in inflammation potential. NALP proteins are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes. The DAPIN domain is necessary and sufficient for suppression of NF-kappa B activation induced by TNF and for inducing IL-1B secretion in collaboration with Caspase-1. It is involved in interaction with PYCARD.
TRUSTED_SUSTAINABILITY
Specifica

Specifica

NALP11
Polyclonal
Unconjugated
NLRP11
CLR19.6; NACHT, leucine rich repeat and PYD containing 11; NACHT, LRR and PYD domains-containing protein 11; NALP11; NLR family pyrin domain containing 11; NLR family, pyrin domain containing 11; NLRP11; NOD17; Nucleotide-binding oligomerization domain protein 17; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11; PAAD- and NACHT-containing protein 10B; PAAD-and NACHT domain-containing protein 10; PAN10; PYPAF6; PYPAF7; PYRIN-containing APAF1-like protein 6
Rabbit
Antigen affinity chromatography
RUO
204801
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Liquid
Immunocytochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P59045
NLRP11
A 15 amino acid peptide near the carboxy terminus of human NALP11.
100 μg
Primary
Human
Antibody
IgG
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