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Invitrogen™ ORMDL1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA521146
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Descrizione
A suggested positive control is SK-N-SH cell lysate. PA5-21146 can be used with blocking peptide PEP-1260.
The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in -gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
Specifica
| ORMDL1 | |
| Polyclonal | |
| Unconjugated | |
| ORMDL1 | |
| Adoplin-1; C730042F17Rik; HSPC202; ORM1-like 1; ORM1-like 1 (S. cerevisiae); ORM1-like protein 1; ORMDL sphingolipid biosynthesis regulator 1; ORMDL1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 100188936, 227102, 94101 | |
| 4°C | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q921I0, Q9P0S3 | |
| ORMDL1 | |
| A 16 amino acid peptide of human ORMDL1. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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