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DiscoverX PathHunter™ CHO-K1 cyno GPR120 β-Arrestin Cell Line
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Quantità:
2 Vials
Descrizione
The PathHunter™ cyno GPR120 β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. free fatty acids) based activation of GPR120 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged cyno GPR120 and EA-tagged β-Arrestin 2. Activation of GPR120 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Cyno version of the protein.
Specifica
Tekniske data
| Assay Entry | β-Arrestin Recruitment |
| Linea cellulare | CHO-K1 |
| Da utilizzare con (applicazione) | Cell Lines |
| Primary Agonist | GW9508 |
| Quantità | 2 Vials |
| Target Entry | cyno GPR120 |
| Numero di accesso | NM_001287319 |
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