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Phospho-Caldesmon (Ser789) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA538263
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Descrizione
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration.
Specifica
| Phospho-Caldesmon (Ser789) | |
| Polyclonal | |
| Unconjugated | |
| CALD1 | |
| CAD, CALD1, CDM, L-caldesmon, Non-muscle caldesmon | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 109624, 25687, 800 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q05682, Q62736 | |
| CALD1 | |
| A synthetic phosphopeptide derived from human Caldesmon around the phosphorylation site of Ser789 (V-T-SP-P-T) | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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