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Phospho-CXCR2 (Ser347) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA538620
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Descrizione
CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Specifica
| Phospho-CXCR2 (Ser347) | |
| Polyclonal | |
| Unconjugated | |
| CXCR2 | |
| CXCR2, CDw128b, CD182 antigen, CMKAR2, CXCR-2, CD182, CXC-R2, IL-8R B, Il-8 receptor b, IL-8 receptor type 2, Il-8rb, IL8R2, IL8RB, IL-8 receptor beta | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 12765, 3579 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P25025, P35343 | |
| CXCR2 | |
| A synthetic phosphopeptide derived from human IL-8R beta/CDw128 beta around the phosphorylation site of Ser347 (R-P-SP-F-V) | |
| 100 μg | |
| Primary | |
| Human, Mouse, Non-human Primate | |
| Antibody | |
| IgG |
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