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Eurofins DiscoverX PKC η Protein, Active
Descrizione
Protein kinase Ch (PKCh) is one of the major protein kinase C isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphophate, the former acting synergistically with Ca2+ to activate protein kinase C (PKC), resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters.
GenBank NM_006255. Translation conflicts with NM_006255, V108L and G109R reported in dbEST BG719560 and BM549890, and L392Q reported in dbEST BI913495, BQ051772 and AU136862.
Specifica
Specifica
| Formulazione | mg/mL of enzyme in 20 mM Tris/HCl pH 7.5, 10 mM benzamidine, 5% glycerol, 1 mM EDTA, 1 mM EGTA, 1 mM PMSF, 0.02% Triton X-100, 0.1% 2-mercaptoethanol. Frozen solution. |
| Peso molecolare | 78.6 kDa |
| Quantità | 10 μg |
| Specie | Human |
| Recombinant | Recombinant |
| Tag proteine | N-terminal 6His |
| Sistema di espressione | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Truncated |
| Purity or Quality Grade | ≥62% |
| Proteine | PKCη (eta), active |
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