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Ubiquitin Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of Ubiquitin.
Marca: Abnova PAB19486.100ug
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Descrizione
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq]
Sequence: KIQDKEGIPPDQQRLIFSpecifica
| Ubiquitin | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of Ubiquitin. | |
| Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal) | |
| FLJ25987/MGC8385 | |
| Rabbit | |
| Immunoaffinity purification | |
| RUO | |
| 7314 | |
| Human, Rat | |
| Lyophilized |
| Immunohistochemistry (PFA fixed), Western Blot | |
| Unconjugated | |
| Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) The optimal working dilution should be determined by the end user. | |
| UBB | |
| UBB | |
| A synthetic peptide corresponding to amino acids 29-45 at N-terminus of human Ubiquitin. | |
| 100 μg | |
| Primary | |
| It identical to the rat and mouse sequences. | |
| Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water to a concentration of 500μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG |
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