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S100A12 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 16630-1-AP-150UL
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Descrizione
S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.Specifica
| S100A12 | |
| Polyclonal | |
| Unconjugated | |
| S100A12 | |
| CAAF1, CAGC, Calgranulin C, CGRP, EN RAGE, ENRAGE, MRP6, Neutrophil S100 protein, p6, Protein S100 A12, S100A12 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 6283 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.37 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P80511 | |
| S100A12 | |
| S100A12 Fusion Protein Ag9961 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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