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Scopolamine hydrobromide trihydrate, 99%

Codice prodotto. 10289593 Sfoglia Tutto Thermo Scientific Chemicals Prodotti
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Quantità:
1 g
5 g
25 g
Imballaggio:
Bottiglia in vetro
Dimensione della confezione:
1g
25g
5g
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Codice prodotto. 10289593

Marca: Thermo Scientific Acros 161750250

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Descrizione

Scopolamine hydrobromide trihydrate, CAS # 6533-68-2, is the trihydrate form of scopolamine hydrobromide that shows competitive anti-muscarinic activity by blocking the actions of endogenous acetylcholine or exogenous agonists. It also shows anti-spasmodic and anti-emetic activities. | CAS: 6533-68-2 | C17H28BrNO7 | 438.32 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Scopolamine hydrobromide trihydrate is a salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), mainly Hyoscyamus niger and Atropa belladonna
• Scopolamine hydrobromide trihydrate, demonstrates competitive anti-muscarinic activity blocking the actions of endogenous acetylcholine or exogenous agonists
• It also shows anti-spasmodic and anti-emetic activities

Applications

• It has been described that scopolamine inhibits muscarinic acetylcholine receptors (mAChRs) with some selectivity for M1 mAChRs
• It is structurally similar to acetylcholine and can antagonize acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves and on smooth muscles (that respond to acetylcholine but lack cholinergic innervation)
• Scopolamine hydrobromide trihydrate can induce amnesia in laboratory animals and so it is frequently used in animal models of memory deficit
• Scopolamine hydrobromide trihydrate is used to induce cognitive deficits in animal models of Alzheimer’s disease
• Scopolamine, has been employed in several studies to understand, identify, and characterize biological targets for Alzheimer's disease

TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 6533-68-2
Formula molecolare C17H28BrNO7
Molecular Weight (g/mol) 438.32
Numero MDL MFCD00150066
InChI Key LACQPOBCQQPVIT-FCFGRTKISA-N
Sinonimo hyoscine hydrobromide trihydrate
PubChem CID 131632304
IUPAC Name hydrogen (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0²,⁴]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate bromide
SMILES [H+].O.O.O.[Br-].CN1[C@H]2CC(C[C@H]1[C@@H]1O[C@H]21)OC(=O)[C@H](CO)C1=CC=CC=C1

Specifica

Materiale o nome chimico Scopolamine hydrobromide trihydrate
Nota nome 99%
Punto di fusione 194.0°C to 197.0°C
Colore White or Colorless
Spettro a infrarossi Authentic
Intervallo percentuale saggio 99%
Imballaggio Bottiglia in vetro
Quantità 25 g
Beilstein 27, 102
Indice di Merck 14, 8406
Condizione di rotazione specifica −27° (20°C c=5,H2O)
Rotazione specifica − 27.00
Informazioni di solubilità Solubility in water: 700g/L water (20°C). Other solubilities: 1g/20 mL alcohol,slightly soluble in chloroform,practically insoluble in ether
Peso formulazione 438.3
Percent Purity 99%
Forma fisica Crystalline Powder or Crystals
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Sicurezza e movimentazione

compliance-icons
Identificativo prodotto
  • Scopolamine hydrobromide trihydrate
 Avvertenza
  • Pericolo
 Categoria di pericolo
  • Tossicità acuta Categoria 1
  • Tossicità acuta Categoria 2
 Indicazioni di pericolo
  • H310-Letale per contatto con la pelle.
  • H330-Letale se inalato.
  • H300-Letale se ingerito.
 Consigli di prudenza
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P310-IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI/un medico/
  • P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P310-Contattare immediatamente un CENTRO ANTIVELENI/un medico .
  • P361-Togliere immediatamente tutti gli indumenti contaminati.
SDS

RUO – Research Use Only

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