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SGK1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA521147
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Descrizione
A suggested positive control is human stomach tissue lysate. PA5-21147 can be used with blocking peptide PEP-1261.
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
Specifica
SGK1 | |
Polyclonal | |
Unconjugated | |
SGK1 | |
serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
20393, 29517, 6446 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry, Western Blot | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
O00141, Q06226, Q9WVC6 | |
SGK1 | |
An 18 amino acid peptide near the carboxy terminus of human SGK1. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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