Invitrogen™ SLC27A1 Polyclonal Antibody

Descrizione

Immunogen sequence: QREGFDPRQT SDRLFFLDLK QGHYLPLNEA VYTRICSGAF Highest antigen sequence indentity to the following orthologs: Rat - 83%, Mouse - 80%.

SLC27A1 is a protein coding gene. Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.