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STK38 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA513831

Dettagli aggiuntivi : Peso : 0.01000kg

Codice prodotto. 10008409

  • 514.00€ / 100µg
Spedizione stimata: 26-06-2024
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Descrizione

Descrizione

STK38 (also known as NDR) or Nuclear Dbf2-related protein is a serine/threonine kinase in the subgroup of the AGC kinase family that is regulated by Mob proteins. Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif. NDR acts as a novel pro-apoptotic kinase, and is a key member of the RASSF1A/MST1 signaling cascade. STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells. STK38 is incorporated into the HIV-1 particles and is cleaved by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity.
Specifica

Specifica

STK38
Polyclonal
PBS with 0.09% sodium azide
Q15208
STK38
KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human STK38
400 μL
Primary
Human
Antibody
IgG
Western Blot
Unconjugated
STK38
5830476G13Rik; 9530097A09Rik; AA617404; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; nuclear Dbf2-related kinase 1; serine/threonine kinase 38; serine/threonine-protein kinase 38; STK38
Rabbit
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
11329
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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