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Thiamphenicol

Codice prodotto. 15495769
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5 g
25 g
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1g
25g
5g
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15495769 5 g 5g
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15405779 25 g 25g
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Codice prodotto. 15495769 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J63575.06
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Beskrivelse

The methyl-sulfonyl analogue of chloramphenicol | CAS: 15318-45-3 | C12H15Cl2NO5S | 356.214 g/mol

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 15318-45-3
Formula molecolare C12H15Cl2NO5S
Molecular Weight (g/mol) 356.214
Numero MDL MFCD00467983
InChI Key OTVAEFIXJLOWRX-NXEZZACHSA-N
Sinonimo thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol
PubChem CID 27200
ChEBI CHEBI:32215
IUPAC Name 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
SMILES CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O

Tekniske data

Materiale o nome chimico Thiamphenicol
Colore White to Yellow
Quantità 5 g
Beilstein 2819542
Indice di Merck 14,9301
Informazioni di solubilità Soluble in acetonitrile or DMF; Slightly soluble in water
Peso formulazione 356.22
Forma fisica Powder

RUO – Research Use Only

Produkttitel
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