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Thermo Scientific Chemicals Trifluoroacetic acid, biochemical grade, 99.5+%

Codice prodotto. 11446947
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Artikelnummer. 11446947 Lieferant Thermo Scientific Chemicals Lieferanten-Nr. A14365.30
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Regulatorischer Hinweis: Dieses Produkt ist ein isoliertes Zwischenprodukt, das gemäß der Verordnung (EG) Nr. 1907/2006 (REACH) transportiert wird. Alle Kunden müssen vor der Lieferung eine Erklärung ausfüllen.

CAS: 76-05-1 | C2HF3O2 | 114.02 g/mol

Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

Solubility
Miscible with ether, acetone, ethanol, benzene, hexane and carbon tetrachloride.

Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 76-05-1
Formula molecolare C2HF3O2
Molecular Weight (g/mol) 114.02
Numero MDL MFCD00004169
InChI Key DTQVDTLACAAQTR-UHFFFAOYSA-N
Sinonimo trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
PubChem CID 6422
ChEBI CHEBI:45892
IUPAC Name trifluoroacetic acid
SMILES OC(=O)C(F)(F)F

Spezifikation

Materiale o nome chimico Trifluoroacetic acid
Punto di fusione -15°C
Punti di ebollizione 72°C to 73°C
Numero UN UN2699
Beilstein 742035
Indice di Merck 14,9681
Informazioni di solubilità Miscible with ether,acetone,ethanol,benzene,hexane and carbon tetrachloride.
Peso formulazione 114.02
Percent Purity ≥99.5%
Grado Biochemical
Densità 1.48
Quantità 250 g
Odore Pungent
Indice di rifrazione 1.284
Sensibilità Hygroscopic
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Produktidentifikator
  • Trifluoroacetic acid
Signalwort
  • Pericolo
Gefahrenkategorie
  • Tossicità acuta Categoria 4
  • PERICOLO A LUNGO TERMINE PER L'AMBIENTE ACQUATICO Cronico 3
  • Lesione oculare grave/irritazione oculare Categoria 1
  • Corrosione/irritazione della pelle Categoria 1A
Gefahrenhinweis
  • H314-Provoca gravi ustioni cutanee e gravi lesioni oculari.
  • H318-Provoca gravi lesioni oculari.
  • H332-Nocivo se inalato.
  • H412-Nocivo per gli organismi acquatici con effetti di lunga durata.
  • EUH071-Corrosivo per le vie respiratorie.
Sicherheitshinweis
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P330+P331-IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.
  • P303+P361+P353-IN CASO DI CONTATTO CON LA PELLE (o con i capelli): togliere immediatamente tutti gli indumenti contaminati. Sciacquare la pelle/fare una doccia.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
  • P310-Contattare immediatamente un CENTRO ANTIVELENI/un medico .
Ergänzende Informationen
  • MIXTURE LIST-Contain: Trifluoroacetic acid

RUO – Research Use Only

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