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Invitrogen™ Ubinuclein 1 Monoclonal Antibody (UBN1-02)
Mouse Monoclonal Antibody
Marca: Invitrogen™ MA110458
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Descrizione
This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.
Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.
Specifica
| Ubinuclein 1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 15mM sodium azide; pH 7.4 | |
| Q9NPG3 | |
| UBN1 | |
| Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| Immunoprecipitation, Western Blot | |
| UBN1-02 | |
| Unconjugated | |
| UBN1 | |
| 1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4 | |
| Mouse | |
| Protein A | |
| RUO | |
| 29855 | |
| 4°C, do not freeze | |
| Liquid |
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