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VLK Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA520875
365.35 EUR valido fino al 2025-03-29
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Allerta:
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Descrizione
A suggested positive control is human lung tissue lysate. PA5-20875 can be used with blocking peptide PEP-0989.
VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy.
Specifica
| VLK | |
| Polyclonal | |
| Unconjugated | |
| PKDCC | |
| Adtk1; AI115348; AW548124; ESTM17; Extracellular tyrosine-protein kinase PKDCC; MAd1; Pkdcc; protein kinase domain containing, cytoplasmic; protein kinase domain containing, cytoplasmic homolog; protein kinase domain-containing protein, cytoplasmic; Protein kinase-like protein SgK493; RGD1311939; SGK493; Sugen kinase 493; vertebrate lonesome kinase; Vlk; X83346 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 106522, 313860, 91461 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q504Y2, Q5RJI4 | |
| PKDCC | |
| A 15 amino acid peptide from near the center of human VLK. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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