missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ZIP1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA521066
Questo articolo non è restituibile.
Consulta la politica di reso
Descrizione
A suggested positive control is mouse kidney tissue lysate. PA5-21066 can be used with blocking peptide PEP-1180.
ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappa-B, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.
Specifica
| ZIP1 | |
| Polyclonal | |
| Unconjugated | |
| Slc39a1 | |
| CGI-08; CGI-71; IRT1; mZIP1; SLC39A1; solute carrier family 39 (zinc transporter), member 1; solute carrier family 39 (zinc transporter), member 3; solute carrier family 39 member 1; Zinc transporter ZIP1; Zinc-iron-regulated transporter-like; Zip1; ZIP-1; ZIRTL; Zrt- and Irt-like protein 1; Zrt/Irt-like protein 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 27173, 30791 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q9NY26, Q9QZ03 | |
| Slc39a1 | |
| A 16 amino acid peptide near the amino terminus of human ZIP1. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
Correzione del contenuto del prodotto
Fornite il vostro feedback sul contenuto del prodotto compilando il modulo sottostante.
Titolo del prodotto
Individuate un'opportunità di miglioramento?Condividi una correzione di contenuto