CAS RN 869288-64-2

IUPAC Nome: 6-[(4-{[(3-methanesulfonylphenyl)methyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl)amino]-1,2,3,4-tetrahydroquinolin-2-one

Sinonimi: 6-[(4-{[(3-methanesulfonylphenyl)methyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl)amino]-3,4-dihydro-1H-quinolin-2-one

Peso molecolare (g/mol): 491.49

Formula molecolare: C22H20F3N5O3S

InChi Key: HESLKTSGTIBHJU-UHFFFAOYSA-N

SMILES: CS(=O)(=O)C1=CC=CC(CNC2=NC(NC3=CC4=C(NC(=O)CC4)C=C3)=NC=C2C(F)(F)F)=C1

1 – 2 di 2 risultati

CAS: 869288-64-2 Formula molecolare: C22H20F3N5O3S

Formula molecolare	C22H20F3N5O3S
CAS	869288-64-2

MedChemExpress PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for purified recombinant catalytic fragment of FAK.

Peso formulazione	491.49
Note sul grado di purezza	Research
Pericolo per la salute 1	H302∣H315∣H319∣H335
Colore	Off-White
Forma fisica	Solid
Molecular Weight (g/mol)	491.49
Conservazione consigliata	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMILES	O=C1NC2=C(C=C(NC3=NC=C(C(F)(F)F)C(NCC4=CC=CC(S(=O)(C)=O)=C4)=N3)C=C2)CC1
Durata utile	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula molecolare	C₂₂H₂₀F₃N₅O₃S
Percent Purity	98.09%
Informazioni di solubilità	DMSO : 25 mg/mL (50.87 mM; Need ultrasonic)
CAS	869288-64-2
Da utilizzare con (applicazione)	Cancer-Kinase/protease
Materiale o nome chimico	PF-573228
Grado	Research