CAS RN 909910-43-6
CAS RN 909910-43-6
IUPAC Nome:
3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)-1H-pyrazole-1-carbothioamide
Sinonimi:
3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)pyrazole-1-carbothioamide
Peso molecolare (g/mol):
421.52
Formula molecolare:
C25H19N5S
InChi Key:
HIJMSZGHKQPPJS-UHFFFAOYSA-N
SMILES:
CC1=CC=CC(=N1)C1=NN(C=C1C1=C2C=CC=CC2=NC=C1)C(=S)NC1=CC=CC=C1
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3
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Tocris Bioscience™ A 83-01
A 83-01 synthesized to Ancillary Material Grade
3
A 83-01, MedChemExpress
MedChemExpress A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.
