MP Biomedicals™ Activated Penetratin™

Descrizione

Applications: Activated PenetratinTM 1 Peptide is a novel tool for peptide and siRNA delivery. It has been successfully used to internalize covalently attached peptides, oligonucleotides, and siRNA. It is sold ready for coupling to peptides or oligonucleotides containing thiol (-SH) functions.
Product Overview: PenetratinTM 1 is a patented 16-amino acid peptide corresponding to the third helix of the homeodomain of antennapedeia protein. This peptide is able to translocate across biological membranes by an energy-independent mechanism (1-3) and has been used successfully to internalize covalently attached peptides (4), oligonucleotides (5) and siRNA (6). Activated PenetratinTM 1 is sold ready for coupling to peptides or oligos containing thiol (-SH) functions. Biotinylated Activated PenetratinTM 1 possesses a biotin group at the C-terminal end allowing the detection of the internalized molecule with an appropriate avidin or streptavidin reagent.
Product Description: The Active PenetratinTM 1 Peptide Transfection reagent features a patented 16 amino acid peptide corresponding to the third helix of the homeodomain of the Antennapedia protein (pAntp) from Drosophila melanogaster.