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AKT2 Mouse anti-Human, Clone: OTI8G8, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Marca: Origene Technologies CF500808
Dettagli aggiuntivi : Peso : 0.05000kg
Descrizione
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer.Specifica
AKT2 | |
Monoclonal | |
Unconjugated | |
AKT2 | |
HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA | |
Mouse | |
Affinity Chromatography | |
RUO | |
208 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI8G8 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P31751 | |
AKT2 | |
Full length human recombit protein of human AKT2 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |