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Aldehyde oxidase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 19495-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899014

  • 140.00€ / 20µL
Spedizione stimata: 15-04-2024
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Descrizione

Descrizione

AOX1 (Aldehyde oxidase 1) is a 1338 amino acid cytoplasmic protein that catalyzes the oxidation of a variety of aldehydes, leading to the production of hydrogen peroxide. Under certain conditions, AOX1 can catalyze the formation of the superoxide free radical. Defects in oxygen radical metabolism have been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS), an autosomal domit neurodegenerative disorder characterized by the death of motor neurons in the spinal cord, brain and brainstem. Significantly, AOX1 is highly expressed in the ventral horn of the spinal cord and the gene that encodes AOX1 is located in a chromosomal region that is frequently found to be implicated in ALS2. This evidence suggests that AOX1 is a candidate gene for ALS2.
Specifica

Specifica

Aldehyde oxidase
Polyclonal
Unconjugated
AOX1
Aldehyde oxidase, aldehyde oxidase 1, AO, AOH1, AOX1
Rabbit
Antigen Affinity Chromatography
RUO
11761, 316, 54349
-20°C
Liquid
Immunofluorescence, Immunoprecipitation, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin)
0.43 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O54754, Q06278, Q9Z0U5
AOX1
Peptide
20 μL
Primary
Mouse, Human, Rat
Antibody
IgG
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