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  6. CD247 with control Mouse anti-Human, Unlabeled, Clone: 8D3, BD

CD247 with control Mouse anti-Human, Unlabeled, Clone: 8D3, BD

Mouse Monoclonal Antibody

216.14€ - 387.34€

Specifica

Antigene CD247 with control
Clone 8D3
Applicazioni Western Blot
Classificazione Monoclonal
Coniugato Unconjugated
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Prodotti 2
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
15806488
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BD Biosciences
551033 		50 μg
ONLINE EXCLUSIVE PRICE
217.00€
216.14€ / Pezzo
Risparmia 0.86€
0.40% Sconto
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BD Biosciences
551034 		150 μg
ONLINE EXCLUSIVE PRICE
388.00€
387.34€ / Pezzo
Risparmia 0.66€
0.17% Sconto
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Description

Description

The T-cell receptor (TCR), expressed by thymus-derived lymphocytes, is a multi-component complex responsible for recognizing antigen in the context of MHC molecules. Ti is the antigen-specific binding component of the TCR. On the majority of peripheral T lymphocytes Ti is present as a disulfide-linked α - β heterodimer. A minor fraction express Ti as a γ- δ heterodimer. The Ti subunits are Ig-like, each containing V and C regions. Ti is noncovalently associated with an invariant set of molecules referred to as the CD3 subunits. CD3 appears early in thymocyte differentiation and remains expressed on all mature T lymphocytes. In the mouse, it consists of five chains, γ(gamma), δ (delta), ε (epsilon), ζ (zeta), and p21. The relative masses of the mouse CD3 chains are 21, 28, 26, 32 (dimer), and 21 kDa respectively.

The 8D3 antibody recognizes the ζ chain of the human and mouse T cell antigen receptor-associated CD3 complex. It reacts with 16 kDa unphosphorylated monomers and 32 kDa unphosphorylated dimers. It does not appear to recognize 21 kDa phosphorylated monomers or 42 kDa phosphorylated dimers. A synthetic peptide corresponding to a region of human CD3 ζ was used as immunogen.

Specifications

Specifications

CD247 with control
Western Blot
Unconjugated
RUO
IgG1
Affinity Purified
CD3ζ chain
8D3
Monoclonal
Mouse
Human, Mouse
Primary
Store undiluted at -20°C.
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