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CD3 Mouse anti-Human, PE, Clone: UCHT1, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 561808

Dettagli aggiuntivi : Peso : 0.02000kg

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Codice prodotto. 15831359

  • 178.00€ / Pezzo
Spedizione stimata: 01-07-2024
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Descrizione

Descrizione

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

Specifica

Specifica

CD3
Monoclonal
PE
Mouse
Affinity Purified
RUO
Human
IgG1 κ
Flow Cytometry
UCHT1
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
25 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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