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CD73 Mouse anti-Human, PE-Cy7, Clone: AD2, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 561258
Dettagli aggiuntivi : Peso : 0.01000kg
Descrizione
The AD2 monoclonal antibody specifically binds to ecto-5’-nucleotidase, a 70 kDa, glycosyl phosphatidylinositol (GPI)-anchored glycoprotein. CD73 is expressed on subsets of T and B lymphocytes, follicular dendritic cells, epithelial cells, endothelial cells and mesenchymal stem cells. Its expression on lymphocytes increases during T and B cell development. CD73 has enzymatic activity and catalyzes the dephosphorylation of adenosine monophosphate (AMP) converting it to adenosine. It has been suggested that CD73 can mediate costimulatory signals in T cell activation and adhesion of lymphocytes to endothelium.
Specifica
| CD73 | |
| Monoclonal | |
| PE-Cyanine7 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Pre-B leukemia cell line | |
| 50 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| AD2 | |
| NT5E; 5' nucleotidase; 5'-NT; E5NT; Ecto-5'-nucleotidase; eN; eNT; NT; NT5 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |