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ATF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 11908-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899283

  • 121.38€ / 20µL

Spedizione stimata: 28-09-2022
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Descrizione

Descrizione

This antibody can recognize all the isoforms of human ATF2. The molecular weight detected is larger than the theoretical value, which may be related to protein modification. About 65-68 kDa band detected in the articles.

The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.
Specifica

Specifica

ATF2
Polyclonal
Unconjugated
ATF2
ATF2, CRE BP1, CREB 2, CREB2, CREBP1, HB16, TREB7
Rabbit
Antigen Affinity Chromatography
RUO
11909, 1386, 81647
-20°C
Liquid
Immunocytochemistry, Western Blot, Immunoprecipitation, Immunofluorescence
0.35 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P15336, P16951, Q00969
Atf2
ATF2 Fusion Protein Ag2581
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali