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BCL11A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 11613-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16898803

  • 129.00€ / 20µL

Spedizione stimata: 23-12-2022
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Descrizione

Descrizione

This is a rabbit polyclonal antibody raised against part chain of N-terminal BCL11A of human origin. There are three isoforms of BCL11A: isoform1 (773 aa), isoform2 (486 aa), and isoform3 (239 aa).

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell maligcies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
Specifica

Specifica

BCL11A
Polyclonal
Unconjugated
BCL11A
B cell CLL/lymphoma 11A, B cell lymphoma/leukemia 11A, BCL11A, COUP TF interacting protein 1, CTIP1, EVI 9, EVI9, HBFQTL5, KIAA1809, ZNF856
Rabbit
Antigen Affinity Chromatography
RUO
14025, 305589, 53335
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.19 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9H165, Q9QYE3
BCL11A
BCL11A Fusion Protein Ag2187
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
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