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BD Pharmingen™ IHC Zinc Fixative
An alternative to formalin fixation of tissue for paraffin embedded sections
Marke: BD 552658
Weitere Details : CAS : 5970-45-6 Peso : 0.62000kg Transport : UN number : 3082 Chem class : 9 Pack group : III
Beschreibung
Ten percent neutral buffered formalin fixes tissue by cross-linking proteins, potentially causing a conformational change or “masking” of the antigenic epitope and leading to reduced or absent antibody reactivity. Different antigen retrieval techniques are used to unmask the epitope; however, many times it is not possible to retrieve the epitope and get optimal immunohistochemical staining. In these situations the use of IHC Zinc fixative, which is a milder fixative than formalin, is recommended.
- Zinc-fixed paraffin embedded sections show very good immunostaining with many leukocytes markers and depict tissue morphology comparable to formalin-fixation
- Use of antigen retrieval techniques on the zinc-fixed paraffin sections may further enhance the antibody reactivity in some cases
There are a few antigens that are not preserved by zinc-fixation. In these situations use of fresh frozen tissue for immunohistochemical staining is the only alternative.
Spezifikation
| 100°C | |
| Room temperature | |
| Fixative | |
| Immunohistochemical staining | |
| Liquid |
| Clear | |
| 10 X | |
| 500mL | |
| 7.2 |
Sicherheit und Handhabung
Produktidentifikator
Signalwort
Gefahrenkategorie
Gefahrenhinweis
Sicherheitshinweis
Ergänzende Informationen
- 10X Zinc Fixative (Formalin Free)
Signalwort
- Pericolo
Gefahrenkategorie
- PERICOLO A LUNGO TERMINE PER L'AMBIENTE ACQUATICO Cronico 2
- Lesione oculare grave/irritazione oculare Categoria 1
- Corrosione/irritazione della pelle Categoria 2
Gefahrenhinweis
- H315-Provoca irritazione cutanea.
- H318-Provoca gravi lesioni oculari.
- H411-Tossico per gli organismi acquatici con effetti di lunga durata.
Sicherheitshinweis
- P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
- P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
- P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
- P501b-Smaltire il prodotto/recipiente in conformità con le disposizioni locali/regionali/nazionali/internazionali.
Ergänzende Informationen
- MIXTURE LIST-Contiene: zinc acetate, zinc chloride