ACROBiosystems Biotinylated Human Latent TGF-beta 3 / Latent TGFB3 Protein, Avitag™
Marca: ACROBiosystems TG3-H8218-200ug
Dettagli aggiuntivi : Peso : 0.00010kg
Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and -beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial-mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.This protein carries an Avi tag at the C-terminus. The protein has a calculated MW of 14.4 kDa.
|Ala 301 - Ser 412|
|Biotinylated Human Latent TGFB3, Avitag (TG3-H8218) is expressed from human 293 cells (HEK293). It contains AA Ala 301 - Ser 412 (Accession # P10600-1).|
|MABSol™ Biotin Labeled Proteins|