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CD3 Molecular Complex Rat anti-Mouse, FITC, Clone: 17A2, BD
Rat Monoclonal Antibody
Marca: BD Biosciences 561798
Dettagli aggiuntivi : Peso : 0.01000kg
Descrizione
The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes. Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells. The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11. This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain. In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells.
Specifica
| CD3 Molecular Complex | |
| Monoclonal | |
| 0.5mg/mL | |
| Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
| γδ TCR-positive T-T hybridoma D1 | |
| 0.1 mg | |
| Immunology | |
| Mouse | |
| IgG2b κ |
| Flow Cytometry | |
| 17A2 | |
| FITC | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.