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CKAP4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Thermo Scientific PA551373
Dettagli aggiuntivi : Peso : 0.02000kg
Descrizione
Immunogen sequence: SRLQHVEDGV LSMQVASARQ TESLESLLSK SQEHEQRLAA LQGRLEGLGS SEADQDGLAS TVRSLGETQL VLYGDVEELK RSVGELPSTV ESLQKVQEQV HTLLSQDQAQ Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 68%.
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14. 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.Specifica
CKAP4 | |
Polyclonal | |
Unconjugated | |
CKAP4 | |
5630400A09Rik; 63 kDa membrane protein; 63-kDa cytoskeleton-linking membrane protein; CKAP4; Climp-63; cytoskeleton associated protein 4; cytoskeleton-associated protein 4; ERGIC-63; LPC-1; p63; transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment; type-II transmembrane protein p63 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
10970 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry, Western Blot | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q07065 | |
CKAP4 | |
Recombinant protein corresponding to Human CKAP4 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only