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ACROBiosystems Cynomolgus MARCO Protein, His Tag

Marca:  ACROBiosystems MAR-C5248-1mg

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 17236320

  • dietro preventivo / 1mg

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Descrizione

Descrizione

MARCO is also known as Scavenger receptor class A member 2 and SCARA2. Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2. MARCO ligation promotes the production of inflammatory mediators by macrophages. MARCO mediated internalization of some ligands prevents their activation of cell surface TLR4 but enables their activation of intracellular TLR3. MARCO contributes to the clearance of apoptotic cells and inhaled bacteria, mast cell mediated silicosis, and the amelioration of allergen or ozone induced lung inflammation. It is required for the organization of the splenic marginal zone and the interaction of splenic macrophages and B cells.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 46.8 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifica

Specifica

XP_005573011.1
46.8 kDa
Cynomolgus MARCO, His Tag (MAR-C5248) is expressed from human 293 cells (HEK293). It contains AA Asn 69 - Ile 520 (Accession # A0A2K5 x 0Z2-1).
-20°C
MARCO
His Tag
Less than 1.0 EU / μg by the LAL method.
Immune Checkpoint Proteins
Powder
1 mg
Asn 69 - Ile 520
MARCO, SCARA2, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2
Unconjugated
PBS, pH7.4
HEK293
Cynomolgus
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SDS
Documenti
Certificati
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