missing translation for 'onlineSavingsMsg'
Learn More

E-cadherin Mouse anti-Human, Porcine, Clone: 6B11F11, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 60335-1-IG-150UL

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 16897435

  • 325.38€ / 150µL

Spedizione stimata: 11-10-2022
per visualizzare lo stock disponibile
Aggiungi al carrello

Descrizione

Descrizione

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintece of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
Specifica

Specifica

E-cadherin
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P12830
CDH1
E-cadherin Fusion Protein Ag15085
150 μL
Primary
Porcine, Human
Antibody
IgG2b
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
6B11F11
Unconjugated
CDH1
Arc 1, Cadherin 1, CAM 120/80, CD324, CDH1, CDHE, E cadherin, ECAD, E-cadherin, Epithelial cadherin, LCAM, UVO, Uvomorulin
Mouse
Protein A
RUO
100048953, 999
-20°C
Liquid
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali