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ACROBiosystems FITC-Labeled Human CD38 Protein, Fc Tag
Marca: ACROBiosystems CD8-HF255-200ug
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.3 kDa. The protein migrates as 65-75 under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifica
| 56.3 kDa | |
| FITC-Labeled Human CD38, Fc Tag (Cat. No. CD8-HF255) is expressed from human HEK293 cells. It contains AA Val 43 - Ile 300 (Accession # P28907-1). It is the FITC labeled form of Human CD38 Protein, Fc Tag (Cat. No. CD8-H5255). | |
| -20°C, avoid light | |
| CD38 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Fluorescent labeled protein |
| 200 μg | |
| Val 43 - Ile 300 | |
| CD38,T10,cADPr hydrolase 1 | |
| FITC | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |