missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ACROBiosystems FITC-Labeled Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free
Marca: ACROBiosystems CDA-HF2W4-25ug
Dettagli aggiuntivi : Peso : 0.00010kg
Beschreibung
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
FITC-Labeled Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free, produced by co-expression of CD8 alpha and CD8 beta, has a calculated MW of 19.5 kDa (CD8 alpha) and 22.1 kDa (CD8 beta). Subunit CD8 alpha is fused with a polyhistidine tag at the C-termSpezifikation
| NP_001759.3 (CD8A)/NP_004922.1 (CD8B) | |
| 25 μg | |
| Ser 22 - Asp 182 (CD8A) and Leu 22 - Pro 170 (CD8B) | |
| CD8 alpha and beta,CD8A and CD8B | |
| FITC | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 19.5 kDa (CD8A) and 22.1 kDa (CD8B) | |
| FITC-Labeled Human CD8A&CD8B; Heterodimer Protein, His Tag&Tag; Free (CDA-HF2W4) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Asp 182 (CD8A) and Leu 22 - Pro 170 (CD8B) (Accession # P01732-1 (CD8A) and P10966-1 (CD8B)). It is the FITC labeled form of Human CD8A&CD8B; Heterodimer Protein, His Tag&Tag; Free (CDA-H52W5). | |
| -20°C, avoid light | |
| CD8 alpha and beta | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Fluorescent labeled protein |